Publications

Changing Prevalence of Lower Airway Infections in Young Children with Cystic Fibrosis.

Authors: Oded Breuer, Andre Schultz, Lidija Turkovic, Nicholas de Klerk, Anthony D. Keil, Siobhain Brennan, Joanne Harrison, Colin Robertson, Philip J. Robinson, Peter D. Sly, Sarath Ranganathan, Stephen M. Stick and Daan Caudri on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in September 2019.

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The cumulative effect of inflammation and infection on structural lung disease in early cystic fibrosis.

Authors: Tim Rosenow, L. Clara Mok, Lidija Turkovic, Luke J. Berry, Peter D. Sly, Sarath Ranganathan, Harm A.W.M. Tiddens, Stephen M. Stick.

Published in the European Respiratory Journal in July 2019.

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Oxidative cross-linking of calprotectin occurs in vivo, altering its structure and susceptibility to proteolysis.

Authors: Teagan S. Hoskina, Jennifer M. Crowther, Jeanette Cheung, Michael J. Epton, Peter D. Sly, Peter A. Elder, Renwick C.J. Dobson, Anthony J. Kettle, Nina Dickerhof.

Published in Redox Biology in June 2019.

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Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes.

Authors: Denby J. Evans, Andre Schultz, Maureen Verheggen, Graham L. Hall, Shannon J. Simpson.

Published in Pediatric Pulmonology in June 2019.

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Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.

Authors: Charles R. Esther Jr., Marianne S. Muhlebach, Camille Ehre, David B. Hill, Matthew C. Wolfgang, Mehmet Kesimer, Kathryn A. Ramsey, Matthew R. Markovetz, Ian C. Garbarine, M. Gregory Forest, Ian Seim, Bryan Zorn, Cameron B. Morrison, Martial F. Delion, William R. Thelin, Diane Villalon, Juan R. Sabater, Lidija Turkovic, Sarath Ranganathan, Stephen M. Stick, Richard C. Boucher.

Published in Science Translational Medicine in April 2019.

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Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease.

Authors: Bob J. Scholte, Hamed Horati, Mieke Veltmana, Rob J. Vreekenc, Luke W. Garratt, Harm A.W.M. Tiddens, Hettie M. Janssens, Stephen M. Stick on behalf of AREST CF. 

Published in the Journal of Cystic Fibrosis in April 2019.

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The role of geographical location and climate on recurrent  pseudomonas infection in young children with Cystic Fibrosis. 

Authors: Ranjana Warrier, Billy Skoric, Suzanna Vidmar, Rosemary Carzino, Sarath Ranganathan.

Published in the Journal of Cystic Fibrosis in April 2019.

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Elastase exocytosis by airway neutrophils is associated with early lung damage in children with cystic fibrosis.

Authors: Camilla Margaroli, Luke W. Garratt, Hamed Horati, A. Susanne Dittrich, Timothy Rosenow, Samuel T. Montgomery, Dario L. Frey, Milton R. Brown, Carsten Schultz, Lokesh Guglani, Anthony Kicic, Limin Peng, Bob J. Scholte, Marcus A. Mall, Hettie M. Janssens, Stephen M. Stick, and Rabindra Tirouvanziam; on behalf of AREST-CF and IMPEDE-CF.

Published in the American Journal of Respiratory and Critical Care Medicine in April 2019.

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Early respiratory viral infections in infants with cystic fibrosis.

Authors: Ashley R. Deschamp, Joseph E. Hatch, James E. Slaven, Netsanet Gebregziabher, Gregory Storch, Graham L. Hall, Stephen Stick, Sarath Ranganathan, Thomas W. Ferkol Stephanie D. Davis.

Published in the Journal of Cystic Fibrosis in February 2019.

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Single-breath washout and association with structural lung disease in children with cystic fibrosis.

Authors: Sophie Yammine, Kathryn A. Ramsey, Billy Skoric, Louise King, Philipp Latzin, Tim Rosenow, Graham L. Hall, Sarath C. Ranganathan, AREST CF.

Published in Pediatratric Pulmonology in January 2019.

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Use of a Primary Epithelial Cell Screening Tool to Investigate Phage Therapy in Cystic Fibrosis.

Authors: Stephanie Trend, Barbara J. Chang, Mark O’Dea, Stephen M. Stick, Anthony Kicic, WAERP, AusREC and AREST CF.

Published in Frontiers in Pharmacology in November 2018.

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Elucidating the Interaction of CF Airway Epithelial Cells and Rhinovirus: Using the Host-Pathogen Relationship to Identify Future Therapeutic Strategies

Authors: Kak-Ming Ling, Luke W. Garratt, Timo Lassmann, Stephen M. Stick, Anthony Kicic, WAERP, AusREC and AREST CF.

Published in Frontiers in Pharmacology in November 2018.

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Predicting disease progression in cystic fibrosis.

Authors: Oded Breuer, Daan Caudri, Stephen Stick and Lidija Turkovic.

Published in Expert Review of Respiratory Medicine in November 2018.

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The association between Staphylococcus aureus and subsequent bronchiectasis in children with cystic fibrosis.

Authors: Daan Caudri, Lidija Turkovic, Jolyn Ng, Nicholas H. de Klerk, Tim Rosenow, Graham L. Hall, Sarath C. Ranganathan, Peter D. Sly, Stephen M. Stick on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in July 2018.

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CrossTalk opposing view: mucosal acidification does not drive early progressive lung disease in cystic fibrosis.

Authors: Stephen M. Stick and Andre Schultz.

Published in the Journal of Physiology in July 2018.

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Clinical utility of surveillance computed tomography scans in infants with cystic fibrosis.

Authors: Katy Newbegin, Katie Pilkington, Shivanthan Shanthikumar, Sarath Ranganathan.

Published in Pediatric Pulmonology in June 2018.

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Interleukin-1 is associated with inflammation and structural lung disease in young children with cystic fibrosis. 

Authors: Samuel T. Montgomery, A. Susanne Dittrich, Luke W. Garratt, Lidija Turkovic, Dario L. Frey, Stephen M. Stick, Marcus A. Mall, Anthony Kicic, AREST CF.

Published in the Journal of Cystic Fibrosis in May 2018.

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The clinical significance of oropharyngeal cultures in young children with cystic fibrosis.

Authors: Oded Breuer, Daan Caudri, Lauren Akesson, Sarath Ranganathan, Stephen M. Stick and André Schultz on behalf of AREST CF.

Published in the European Respiratory Journal in April 2018.

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The potential of antisense oligonucleotide therapies for inherited childhood lung diseases. 

Authors: Kelly M. Martinovich, Nicole C. Shaw, Anthony Kicic, André Schultz, Sue Fletcher, Steve D. Wilton and Stephen M. Stick.

Published in Molecular and Cellular Pediatrics in February 2018.

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The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials. 

Authors: Rachel E. Foong, Alana J. Harper, Billy Skoric, Louise King, Lidija Turkovic, Miriam Davis, Charles C. Clem, Tim Rosenow, Stephanie D. Davis, Sarath Ranganathan, Graham L. Hall, and Kathryn A. Ramsey on behalf of AREST CF.

Published in the European Respiratory Journal Open Research in February 2018.

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Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells. 

Authors: Erika N. Sutanto, Amelia Scaffidi, Luke W. Garratt, Kevin Looi, Clara J. Foo, Michela A. Tessari, Richard A. Janssen, David F. Fischer, Stephen M. Stick, Anthony Kicic, on behalf of AREST CF.

Published in PLoS One in January 2018.

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Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children.

Authors: Marianne S. Muhlebach, Bryan T. Zorn, Charles R. Esther, Joseph E. Hatch, Conor P. Murray, Lidija Turkovic, Sarath C. Ranganathan, Richard C. Boucher, Stephen M. Stick, Matthew C. Wolfgang

Published in PLoS Pathogens in January 2018.

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Quantification of CT bronchiectasis and its relationship to ventilation in cystic fibrosis.

Author: Tim Rosenow

Published in Thorax in January 2018.

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Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics.

Authors: Kelly M. Martinovich, Thomas Iosifidis, Alysia G. Buckley, Kevin Looi , Kak-Ming Ling, Erika N. Sutanto, Elizabeth Kicic-Starcevich, Luke W. Garratt, Nicole C. Shaw, Samuel Montgomery, Francis J. Lannigan, Darryl A. Knight, Anthony Kicic and Stephen M. Stick.

Published in Scientific Reports in December 2017.

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Airway surface liquid pH is not acidic in children with cystic fibrosis.

Authors: André Schultz, Ramaa Puvvadi, Sergey M. Borisov, Nicole C. Shaw, Ingo Klimant, Luke J. Berry, Samuel T. Montgomery, Thien Nguyen, Silvia M. Kreda, Anthony Kicic, Peter B. Noble, Brian Button & Stephen M. Stick.

Published in Nature Communications in November 2017.

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Association of Antibiotics, Airway Microbiome, and Inflammation in
Infants with Cystic Fibrosis.

Authors: Jessica E. Pittman, Kristine M. Wylie, Kathryn Akers, Gregory A. Storch, Joseph Hatch, Jane Quante, Katherine B. Frayman, Nadeene Clarke, Miriam Davis, Stephen M. Stick, Graham L. Hall, Gregory Montgomery, Sarath Ranganathan, Stephanie D. Davis, Thomas W. Ferkol and AREST CF.

Published in the Annals of the American Thoracic Society in October 2017.

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The AREST CF experience in biobanking — More than just tissues, tubes and time.

Authors: Luke W. Garratt, Anthony Kicic, Colin Robertson, Sarath Ranganathan, Peter D. Sly, Stephen M. Stick on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in September 2017.

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Quantitative Assessment of Airway Dimensions in Young Children with Cystic Fibrosis Lung Disease using CT. 

Authors: Wieying Kuo, Thomas Soffers, Eleni-Rosalina Andrinopoulou, Tim Rosenow, Sarath Ranganathan, Lidija Turkovic, Stephen M. Stick, Harm A.W.M. Tiddens on behalf of AREST CF.

Published in Pediatric Pulmonology in September 2017.

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Multiple Breath Washout Outcomes Are Sensitive to Inflammation and Infection in Children with Cystic Fibrosis.

Authors: Kathryn A. Ramsey, Rachel E. Foong, Jasmine Grdosic, Alana Harper, Billy Skoric, Charles Clem, Miriam Davis, Lidija Turkovic, Stephen M. Stick1, Stephanie D. Davis, Sarath C. Ranganathan, and Graham L. Hall on behalf of AREST CF.

Published in Annals of the American Thoracic Society in September 2017.

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Early Lung Disease in Infants and Preschool Children with Cystic Fibrosis. What Have We Learned and What Should We Do about It?

Authors: Sarath C. Ranganathan, Graham L. Hall, Peter D. Sly, Stephen M. Stick, and Tonia A. Douglas on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in June 2017. 

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Air Trapping in Early Cystic Fibrosis Lung Disease - Does CT Tell a Full Story?

Authors: Tim Rosenow, Kathryn Ramsey, Lidija Turkovic, Conor P. Murray, L. Clara Mok, Graham L. Hall, Stephen M. Stick on behalf of AREST CF.

Published in Pediatric Pulmonology in June 2017.

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Lack of small colony variants of Staphylococcus aureus from
lower respiratory tract specimens.

Authors: Rosemary Carzino, Emily Hart, Philip Sutton, Louise King, Sarath Ranganathan on behalf of AREST CF.

Published in Pediatric Pulmonology in May 2017.

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Investigating self‐efficacy, disease knowledge and adherence to treatment in adolescents with cystic fibrosis.

Authors: Nicholas R Faint, Janelle M Staton, Stephen M Stick, Juliet M Foster and André Schultz.

Published in the Journal of Paediatrics and Child Health in May 2017.

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The Effect of 100% Oxygen on Tidal Breathing Parameters in Preschool Children.

Authors: Rachel E. Foong, Alana J. Harper, Graham L. Hall and Kathryn A. Ramsey on behalf of AREST CF.

Published in the European Respiratory Journal in March 2017.

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Sialic acid-to-urea ratio as a measure of airway surface hydration.

Authors: Charles R. Esther, Jr., David B. Hill, Brian Button, Shuai Shi, Corey Jania, Elizabeth A. Duncan, Claire M. Doerschuk, Gang Chen, Sarath Ranganathan, Stephen M. Stick and Richard C. Boucher.

Published in the American Journal of Physiology in March 2017.

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Induced sputum to detect lung pathogens in young children with cystic fibrosis.

Authors: Pamela D' Sylva, Daan Caudri, Nicole Shaw, Lidija Turkovic, Tonia Douglas, Jane Bew, Anthony D. Keil, Stephen Stick, André Schultz.

Published in Pediatric Pulmonology in February 2017. 

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Effect of Posture on Lung Ventilation distribution and Associations with Structure in Children with Cystic Fibrosis.

Authors: Kathryn A. Ramsey, Caroline McGirr, Stephen M. Stick, Graham L. Hall, Shannon J. Simpson on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in January 2017.

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Hypoxia and sterile inflammation in cystic fibrosis airways: mechanisms and potential therapies.

Authors: Samuel T. Montgomery, Marcus A. Mall, Anthony Kicic, Stephen M. Stick on behalf of AREST CF.

Published in the European Respiratory Journal in January 2017.

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Metabolomic Biomarkers Predictive of Early Structural Lung Disease in Cystic Fibrosis.

Authors: Charles R. Esther Jr, Lidija Turkovic, Tim Rosenow, Marianne S. Muhlebach, Richard C. Boucher, Sarath Ranganathan and Stephen M. Stick on behalf of AREST CF

Published in the European Respiratory Journal in December 2016. 

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Of Pigs, Mice, and Men: Understanding Early Triggers of Cystic Fibrosis Lung Disease.

Authors: Stephen M. Stick, Anthony Kicic and Sarath Ranganathan.

Published in the American Journal of Respiratory and Critical Care Medicine in October 2016. 

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Respiratory Infection Rates Differ Between Geographically Distant Paediatric Cystic Fibrosis Cohorts.

Authors: Kathryn A. Ramsey, Emily Hart, Lidija Turkovic, Marc Padros-Goossens, Stephen M. Stick and Sarath C. Ranganathan on behalf of AREST CF.

Published in European Respiratory Society Open Research in September 2016. 

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Diagnosis and Early Life Risk Factors for Bronchiectasis in Cystic Fibrosis: A Review.

Authors: Peter D. Sly and Claire E. Wainwright

Published in the Expert Review of Respiratory Medicine in September 2016.

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Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability.

Authors: Kevin Looi, Niamh M. Troy, Luke W.Garratt, Thomas Iosifidis, Anthony Bosco, Alysia G. Buckley, Kak-Ming Ling, Kelly M. Martinovich, Elizabeth Kicic-Starcevich, Nicole C.Shaw, Erika N.Sutanto, Graeme R. Zosky, Paul J. Rigby, Alexander N. Larcombe, Darryl A.Knight, Anthony Kicic and Stephen M.Stick.

Published in Experiemental Lung Research in August 2016.

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Bile signalling promotes chronic respiratory infections and  antibiotic tolerance.

Authors:  F. Jerry Reen, Stephanie Flynn, David F. Woods, Niall Dunphy, Muireann Ní Chróinín, David Mullane, Stephen Stick, Claire Adams & Fergal O’Gara.

Published in Scientific Report in July 2016.

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Dissecting the regulation of bile-induced biofilm formation in Staphylococcus aureus.

Authors: Dulantha Ulluwishewa, Liang Wang, Callen Pereira, Stephanie Flynn, Elizabeth Cain, Stephen Stick, F. Jerry Reen, Joshua P. Ramsay and Fergal O’Gara. 

Published in Microbiology in May 2016.

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Parental Experience of Information and Education Processes Following Diagnosis of Their Infant With Cystic Fibrosis Via Newborn Screening.

Authors: Melanie Jessup, Tonia Douglas, Lynn Priddis, Cindy Branch-Smith, Linda Shields on behalf of AREST CF.

Published in the Journal of Pediatric Nursing in May 2016.

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Multiple breath washout cannot be used for tidal breath parameter analysis in infants.

Authors: Georgia L. Banton, Graham L. Hall, Mark Tan, Billy Skoric, Sarath C. Ranganathan, Peter J. Franklin, J. Jane Pillow, Sven M. Schulzke and Shannon J. Simpson.

Published in Pediatric Pulmonology May 2016.

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Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase.

Authors: Luke W. Garratt, Erika N. Sutanto, Kak-Ming Ling, Kevin Looi, Thomas Iosifidis, Kelly M. Martinovich, Nicole C. Shaw, Alysia G. Buckley, Elizabeth Kicic-Starcevich, Francis J. Lannigan, Darryl A. Knight, Stephen M. Stick and Anthony Kicic on behalf of AREST CF.

Published in the American Journal of Respiratory Cell and Molecular Biology in March 2016. 

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Lung Clearance Index and Structural Lung Disease on Computed Tomography in Early Cystic Fibrosis.

Authors: Kathryn A. Ramsey, Tim Rosenow, Lidija Turkovic, Billy Skoric, Georgia Banton, Anne-Marie Adams, Shannon J. Simpson, Conor Murray, Sarath C. Ranganathan, Stephen M. Stick and Graham L. Hall on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in January 2016.

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Psychosocial characteristics and predictors of health-care use in families of young children with cystic fibrosis in Western Australia.

Authors: Tonia Douglas, Jennifer Green, Judy Park, Lidija Turkovic, John Massie and Linda Shields.

Published in the Journal of Paediatrics and Child Health in January 2016.

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Early Lung Surveillance of Cystic Fibrosis: what have we learnt?

Authors: Rachel E Foong, Tim Rosenow, Luke W Garratt & Graham L Hall.

Published in the Expert Review of Respiratory Medicine in January 2017.

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Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infection.

Authors: Shannon J. Simpson, Sarath Ranganathan, Judy Park, Lidija Turkovic, Roy M. Robins-Browne, Billy Skoric, Kathryn A. Ramsey, Tim Rosenow, Georgia L. Banton, Luke Berry, Stephen M. Stick and Graham L. Hall on behalf of AREST CF.

Published in the European Respiratory Journal in December 2015.

 

Excess Risk of Cancer from Computed Tomography Scan Is Small but Not So Low as to Be Incalculable.

Authors: Tim Rosenow, Merel Oudraad, Conor Murray, Lidija Turkovic, Wieying Kuo, Marleen de Bruijne, Sarath Ranganathan, Harm Tiddens, Stephen Stick. 

Published in the American Journal of Respiratory and Critical Care Medicine in December 2015.

 

Impact of lung disease on respiratory impedance in young children with cystic fibrosis.

Authors: Kathryn Ramsey, Sarath C Ranganathan, Catherine L Gangell, Lidija Turkovic, Judy Park, Billy Skoric, Stephen M Stick, Peter D Sly, Graham L Hall.

Published in the European Respiratory Journal December 2015.

 

An epilogue to lung function and lung disease: state-of-the-art 2015.

Authors: Charles G Irvin, Graham L Hall.

Published in Respirology in October 2015.

 

Respiratory tract exacerbations revisited: ventilation, inflammation, perfusion, and structure (VIPS) monitoring to redefine treatment.

Authors: Harm A.W.M. Tiddens, Stephen M. Stick, Jim M. Wild, Pierluigi Ciet, Geoffrey J.M. Parker, Armin Koch, and Jens Vogel-Claussen.

Published in Pediatric Pulmonology October 2015.

 

Biomarkers in Paediatric Cystic Fibrosis Lung Disease.

Authors: Kathryn A. Ramsey, Andre Schultz, Stephen M. Stick.

Published in the Paediatric Respiratory Reviews in September 2015.

 

Oxidation of calprotectin by hypochlorous acid prevents chelation of essential metal ions and allows bacterial growth: Relevance to infections in cystic fibrosis.

Authors: Nicholas J. Magon, Rufus Turner, Richard B.Gearry, Mark B. Hampton, Peter D. Sly, Anthony J. Kettle.

Published in Free Radical Biology and Medicine in September 2015.

 

Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis.

Authors: Luke W. Garratt, Erika N. Sutanto, Kak-Ming Ling, Kevin Looi, Thomas Iosifidis, Kelly M. Martinovich, Nicole C. Shaw, Elizabeth Kicic-Starcevich, Darryl A. Knight, Sarath Ranganathan, Stephen M. Stick and Anthony Kicic on behalf of AREST CF.

Published in the European Respiratory Journal in August 2015.

 

Protocol for a study of the psychosocial determinants of health in early childhood among children with cystic fibrosis.

Authors: Tonia Douglas, Brigid Jordan, Lynn Priddis, Vicki Anderson, Jane Sheehan, Robert T. Kane, John Massie, Cindy Branch-Smith and Linda Shields on behalf of AREST CF.

Published in the Journal of Advanced Nursing in July 2015.

 

Reversibility of trapped air on chest computed tomography in cystic fibrosis patients.

Authors: Martine Loeve, Tim Rosenow, Vladlena Gorbunova, Wim C.J. Hop, Harm A.W.M. Tiddens, Marleen de Bruijne.

Published in the European Journal of Radiology in June 2015

 

Early pulmonary inflammation and lung damage in children with cystic fibrosis.

Authors: Andre Schultz, Stephen Stick.

Published in Respirology in May 2015.

 

PRAGMA-CF: a Quantitative Structural Lung Disease CT Outcome in Young Children with Cystic Fibrosis.

Authors: Tim Rosenow, Merel C. J. Oudraad, Conor P. Murray, Lidija Turkovic, Wieying Kuo, Marleen de Bruijne, Sarath C. Ranganathan, Harm A. W. M. Tiddens, and Stephen M. Stick on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in May 2015.

 

Defining the appropriate waiting time between multiple-breath nitrogen washout measurements.

Authors: Elizabeth R Salamon, Kevin R Gain, Graham L Hall.

Published in the European Respiratory Journal in May 2015.

Feasibility of parental collected nasal swabs for virus detection in young children with cystic fibrosis.

Authors: C.L. Gangell, C. Shackleton, S. Poreddy, J. Kappers, J.E. Gaydon, T.P. Sloots, S.M. Stick, S.C. Ranganathan, P.D. Sly.

Published in the Journal of Cystic Fibrosis in December 2014.

 

Lung clearance index during hospital admission in school-age children with cystic fibrosis.

Authors: Liam Welsh, Christopher Nesci, Haily Tran, Marisol Tomai, Sarath Ranganathan.

Published in the Journal of Cystic Fibrosis in December 2014.

 

Early respiratory infection is associated with reduced spirometry in children with cystic fibrosis.

Authors: Kathryn A. Ramsey, Sarath Ranganathan, Judy Park, Billy Skoric, Anne-Marie Adams, Shannon J. Simpson, Roy M. Robins-Browne, Peter J. Franklin, Nick H. de Klerk, Peter D. Sly, Steve M. Stick and Graham L. Hall on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in November 2014.

 

Determinants of culture success in an airway epithelium sampling program of young children with cystic fibrosis.

Authors: Luke W. Garratt, Erika N. Sutanto, Clara J. Foo, Kak Ming Ling, Kevin Looi, Elizabeth Kicic-Starcevich, Thomas Iosifidis, Kelly M. Martinovich, Francis J. Lannigan, Stephen M. Stick, and Anthony Kicic on behalf of AREST CF.

Published in Experimental Lung Research in November 2014.

 

Antibiotic management of lung infections in cystic fibrosis. II. Nontuberculous mycobacteria, anaerobic bacteria, and fungi.

Authors: James F. Chmiel, Timothy R. Aksamit, Sanjay H. Chotirmall, Elliott C. Dasenbrook, J. Stuart Elborn, John J. LiPuma, Sarath C. Ranganathan, Valerie J. Waters, and Felix A. Ratjen.

Published in the Annals of the American Thoracic Society in October 2014. 

 

Increased rate of lung function decline in Australian adolescents with cystic fibrosis.

Authors: Liam Welsh, Colin F. Robertson and Sarath C. Ranganathan.

Published in Pediatric Pulmonology in September 2014.

 

Interpretation of lung function in infants and young children with cystic fibrosis.

Authors: Kathryn Ramsey, Sarath Ranganathan.

Published in Respirology in August 2014. 

 

Oxidation contributes to low glutathione in the airways of children with cystic fibrosis.

Authors: Anthony J. Kettle, Rufus Turner, Catherine L. Gangell, D. Timothy Harwood, Irada S. Khalilova, Anna L. Chapman, Christine C. Winterbourn and Peter D. Sly on behalf of AREST CF.

Published in The European Respiratory Journal in July 2014.

 

Multi-modality monitoring of cystic fibrosis lung disease: the role of chest computed tomography.

Authors: Harm A.W.M. Tiddens, Stephen M. Stick, Stephanie Davis.

Published in Paediatric respiratory reviews in March 2014.

 

Airway, but not serum or urinary, levels of YKL-40 reflect inflammation in early cystic fibrosis lung disease.

Authors: Emmanuelle Fantino, Catherine L Gangell, Dominik Hartl and Peter D Sly on behalf of AREST CF.

Published in BMC Pulmonary Medicine in February 2014.

 

Induced sputum compared to bronchoalveolar lavage in young, non-expectorating cystic fibrosis children.

Authors: Hannah Blau, Barry Linnane, Rosemary Carzino, Esta-Lee Tannenbaum, Billy Skoric, Philip J. Robinson, Colin Robertson, Sarath C. Ranganathan.

Published in the Journal of Cystic Fibrosis in January 2014. 

Staphylococcus aureus in early cystic fibrosis lung disease.

Authors: John K. Wong, Sarath C. Ranganathan and Emily Hart on behalf of
AREST CF.

Published in Pediatric Pulmonology in December 2013.

 

Scoping review of the literature about family-centered care with caregivers of children with cystic fibrosis.

Authors: Linda Shields, Ailsa Munns, Marjory Taylor, Lynn Priddis, Judy Park, Tonia Douglas on behalf of AREST CF.

Published in Neonatal, Paediatric and Child Health Nursing in November 2013.

 

Assessment of early bronchiectasis in young children with cystic fibrosis is dependent on lung volume. 

Authors: Lauren S. Mott,  Karla G. Graniel, Judy Park, Nicholas H. de Klerk, Peter D. Sly, Conor P. Murray, Harm A. W. M. Tiddens and Stephen M. Stick on behalf of AREST CF.

Published in Chest in October 2013.

 

Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?

Authors: Martine Loeve, Gabriel P. Krestin, Margaret Rosenfeld, Marleen de Bruijne, Stephen M. Stick and Harm A. Tiddens.

Published in The European Respiratory Journal in September 2013.

 

Early intervention studies in infants and preschool children with cystic fibrosis: are we ready?

Authors: Stephen Stick, Harm Tiddens, Paul Aurora, Per Gustafsson, Sarath Ranganathan, Paul Robinson, Margaret Rosenfeld, Peter Sly and Felix Ratjen.

Published in the European Respiratory Journal in August 2013.

 

Distribution of early structural lung changes due to cystic fibrosis detected with chest computed tomography. 

Authors: Lauren S. Mott, Judy Park, Catherine L. Gangell, Nicholas H. de Klerk, Peter D. Sly, Conor P. Murray and Stephen M. Stick on behalf of AREST CF.

Published in the Journal of Pediatrics in July 2013.

 

Novel end points for clinical trials in young children with cystic fibrosis.

Authors: Shannon J Simpson, Lauren S Mott, Charles R Esther Jr, Stephen M Stick and Graham L Hall.

Published in Expert Review of Respiratory Medicine in June 2013.

 

Risk Factors for Bronchiectasis in Children with Cystic Fibrosis.

Authors: Peter D. Sly, Catherine L. Gangell, Linping Chen, Robert S. Ware,
Sarath Ranganathan, Lauren S. Mott, Conor P. Murray and Stephen M. Stick on behalf of AREST CF.

Published in The New England Journal of Medicine in May 2013.

 

Geographical differences in first acquisition of Pseudomonas aeruginosa in cystic fibrosis.

Authors: Sarath C. Ranganathan, Billy Skoric, Kay A. Ramsay, Rosemary Carzino, Anne-Marie Gibson, Emily Hart, Jo Harrison, Scott C. Bell, and Timothy J. Kidd on behalf of AREST-CF.

Published in the Annals of the American Thoracic Society in April 2013.

 

An official American Thoracic Society workshop report: optimal lung function tests for monitoring cystic fibrosis, bronchopulmonary dysplasia, and recurrent wheezing in children less than 6 years of age.

Authors: Margaret Rosenfeld, Julian Allen, Bert H. G. M. Arets, Paul Aurora, Nicole Beydon, Claudia Calogero, Robert G. Castile, Stephanie D. Davis, Susanne Fuchs, Monika Gappa, Per M. Gustaffson, Graham L. Hall, Marcus H. Jones, Jane C. Kirkby, Richard Kraemer, Enrico Lombardi, Sooky Lum, Oscar H. Mayer, Peter Merkus, Kim G. Nielsen, Cara Oliver, Ellie Oostveen, Sarath Ranganathan, Clement L. Ren, Paul D. Robinson, Paul C. Seddon, Peter D. Sly, Marianna M. Sockrider, Samatha Sonnappa, Janet Stocks, Padmaja Subbarao, Robert S. Tepper, Daphna Vilozni; on behalf of the American Thoracic Society Assembly on Pediatrics Working Group on Infant and Preschool Lung Function Testing

Published in Annals of the American Thoracic Society in April 2013.

 

 

Consensus statement for inert gas washout measurement using multiple- and single-breath tests. 

Authors: Paul D. Robinson, Philipp Latzin, Sylvia Verbanck, Graham L. Hall, Alexander Horsley, Monika Gappa, Cindy Thamrin, Hubertus G.M. Arets, Paul Aurora, Susanne I. Fuchs, Gregory G. King, Sooky Lum, Kenneth Macleod, Manuel Paiva, Jane J. Pillow, Sarath Ranganathan, Felix Ratjen, Florian Singer, Samatha Sonnappa, Janet Stocks, Padmaja Subbarao, Bruce R. Thompson and Per M. Gustafsson

Published in the European Respiratory Journal in March 2013.

Progression of early structural lung disease in young children with cystic fibrosis assessed using CT.

Authors: Lauren S Mott, Judy Park, Conor P Murray, Catherine L Gangell, Nicholas H de Klerk, Philip J Robinson, Colin F Robertson, Sarath C Ranganathan, Peter D Sly, Stephen M Stick on behalf of AREST CF.

Published in Thorax in June 2012.

 

Small macrophages are present in early childhood respiratory disease.

Authors: Luke W. Garratt, Adam K.A. Wright, Sarath C. Ranganathan, Jonathan Grigg and Peter D. Sly on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in May 2012.

 

A fat lot of good: balance and trends in fat intake in children with cystic fibrosis.

Authors: C. Smith, A. Winn, P. Seddon, S. Ranganathan.

Published in Journal of cystic fibrosis in March 2012.

 

Comparison of the US and Australian cystic fibrosis registries: the impact of newborn screening.

Authors: Bradley Martin, Michael S. Schechter, Adam Jaffe, Peter Cooper, Scott C. Bell, Sarath Ranganathan.

Published in Pediatrics in February 2012.

 

Australian epidemic strain pseudomonas (AES-1) declines further in a cohort segregated cystic fibrosis clinic.

Authors: Amanda L. Griffiths, Danielle F. Wurzel, Phil J. Robinson, Rosemary Carzino, John Massie.

Published in Journal of cystic fibrosis in January 2012.

Inflammatory responses to individual microorganisms in the lungs of children with cystic fibrosis.

Authors:  Catherine Gangell, Samantha Gard, Tonia Douglas, Judy Park, Nicholas de Klerk, Tony Keil, Siobhain Brennan, Sarath Ranganathan, Roy Robins-Browne and Peter D. Sly on behalf of AREST CF.

Published in Clinical Infectious Diseases in September 2011. 

 

Early detection of lung function abnormalities in young children with Cystic Fibrosis.

Authors: Catherine G Gangell and Graham L Hall on behalf of AREST CF.

Published in The Annals of Respiratory Medicine in August 2011. 

 

Air trapping on chest CT is associated with worse ventilation distribution in infants with cystic fibrosis diagnosed following newborn screening.

Authors: Graham L. Hall, Karla M. Logie, Faith Parsons, Sven M. Schulzke, Gary Nolan, Conor Murray, Sarath Ranganathan, Phil Robinson, Peter D. Sly, Stephen M. Stick on behalf of AREST CF.

Published in PloS one in August 2011. 

 

Early detection of lung function abnormalities in young children with Cystic Fibrosis.

Authors: Catherine G Gangell and Graham L Hall on behalf of AREST CF.

Published in The Annals of Respiratory Medicine in August 2011

 

Infection, inflammation, and lung function decline in infants with cystic fibrosis.

Authors: Naveen Pillarisetti, Elizabeth Williamson, Barry Linnane, Billy Skoric, Colin F. Robertson, Phil Robinson, John Massie, Graham L. Hall, Peter Sly, Stephen Stick and Sarath Ranganathan on behalf of AREST CF.

Published in American Journal of Respiratory and Critical Care Medicine in July 2011. 

 

Innate inflammatory responses of pediatric cystic fibrosis airway epithelial cells: effects of nonviral and viral stimulation.

Authors: Erika N. Sutanto, Anthony Kicic, Clara J. Foo, Paul T. Stevens, David Mullane, Darryl A. Knight and Stephen M. Stick on behalf of AREST CF.

Published in the American Journal of Respiratory Cell and Molecular Biology in June 2011. 

 

Exciting new clinical trials in cystic fibrosis: infants need not apply.

Authors: Stephen M Stick, Peter D Sly.

Published in American Journal of Respiratory and Critical Care Medicine in June 2011.

 

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis.

Authors: Sarath C Ranganathan, Faith Parsons, Catherine Gangell, Siobhan Brennan, Stephen M Stick, Peter D Sly on behalf of AREST CF.

Published in Thorax in May 2011. 

 

Randomised controlled trials in cystic fibrosis: what, when and how?

Authors: P.D. Sly, R.S. Ware, N. de Klerk and S.M. Stick.

Published in The European Respiratory Journal in May 2011. 

 

Intervention trials and ventilation distribution in mild cystic fibrosis lung disease: will it all come out in the wash?

Authors: GL Hall , J Stocks.

Published in The European Respiratory Journal in April 2011. 

 

Cyanide in bronchoalveolar lavage is not diagnostic for Pseudomonas aeruginosa in children with cystic fibrosis.

Authors: M.D.Stutz, C.L.Gangell, L.J.Berry, L.W.Garratt, B.Sheil and P.D.Sly on behalf of AREST CF.

Published in the European Respiratory Journal in March 2011.

Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis.

Authors: Eline Thomson, Siobhain Brennan, Revathy Senthilmohan, Catherine L. Gangell, Anna L. Chapman, Peter D. Sly and Anthony J. Kettle on behalf of AREST CF.

Published in Free Radical Biology and Medicine in November 2010. 

 

Value of serology in predicting Pseudomonas aeruginosa infection in young children with cystic fibrosis.

Authors: Tonia A Douglas, Siobhain Brennan, Luke Berry, Kaye Winfield, Claire E Wainwright, Keith Grimwood, Stephen M Stick and Peter D Sly on behalf of AREST CF and the ACFBAL Trial.

Published in Thorax in November 2010. 

 

Monocytes from children with clinically stable cystic fibrosis show enhanced expression of Toll-like receptor 4.

Authors: Nina C. Sturges, Matthew E. Wikstrom, Kaye R. Winfield, Samantha E. Gard, Siobhain Brennan, Peter D. Sly and John W. Upham on behalf of AREST CF.

Published in Pediatric Pulmonology in September 2010. 

 

Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storage. 

Authors: Luke J. Berry, Barbara Sheil, Luke Garratt and Peter D. Sly on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in September 2010. 

 

Early bronchiectasis in cystic fibrosis detected by surveillance CT.

Authors: Naveen Pillarisetti, Barry Linnane and Sarath Ranganathan on behalf of AREST CF.

Published in Respirology in August 2010. 

 

Interpretation of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine is adversely affected by methodological inaccuracies when using a commercial ELISA.

Authors: Luke W. Garratt, Vilas Mistry, Rajinder Singh, Jatinderpal Kaur Sandhu, Barbara Sheil, Marcus S. Cooke, Peter D. Sly and on behalf of AREST CF.

Published in Free Radical Biology and Medicine in June 2010. 

 

Lung function testing in preschool-aged children with cystic fibrosis in the clinical setting.

Authors: Catherine L. Gangell, Graham L. Hall, Stephen M. Stick and Peter D. Sly on behalf of AREST CF.

Published in Pediatric Pulmonology in May 2010. 

Bronchiectasis in infants and preschool children diagnosed with cystic fibrosis after newborn screening.

Authors: Stephen M. Stick, Siobhain Brennan, Conor Murray, Tonia Douglas, Britta S. von Ungern-Sternberg, Luke W. Garratt, Catherine L. Gangell, Nicholas De Klerk, Barry Linnane, Sarath Ranganathan, Phillip Robinson, Colin Robertson and Peter D. Sly on behalf of AREST CF.

Published in the The Journal of Pediatrics in November 2009. 

 

Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis.

Authors: S. Brennan, P.D. Sly, C.L. Gangell, N. Sturges, K. Winfield, M. Wikstrom, S. Gard and J.W. Upham on behalf of AREST CF.

Published in the European Respiratory Journal in September 2009. 

 

Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening.

Authors: Peter D. Sly, Siobhain Brennan, Catherine Gangell, Nicholas de Klerk, Conor Murray, Lauren Mott, Stephen M. Stick, Philip J. Robinson, Colin F. Robertson and Sarath C. Ranganathan on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in July 2009. 

 

Bronchiectasis in an asymptomatic infant with cystic fibrosis diagnosed following newborn screening.

Authors: Lauren S. Mott, Catherine L. Gangell, Conor P. Murray, Stephen M. Stick and Peter D. Sly on behalf of AREST CF.

Published in the Journal of Cystic Fibrosis in July 2009. 

 

Acquisition and eradication of P. aeruginosa in young children with cystic fibrosis.

Authors: T.A. Douglas, S. Brennan, S. Gard, L. Berry, C. Gangell, S.M. Stick,
B.S. Clements and P.D. Sly.

Published in the European Respiratory Journal in February 2009. 

 

Vitamin D in infants with cystic fibrosis diagnosed by newborn screening.

Authors: Liza A Neville and Sarath C Ranganathan.

Published in the Journal of Paediatrics and Child Health in January 2009.

Lung function in infants with cystic fibrosis diagnosed by newborn screening.

Authors: Barry M. Linnane, Graham L. Hall, Gary Nolan, Siobhan Brennan, Stephen M. Stick, Peter D. Sly, Colin F. Robertson, Philip J. Robinson, Peter J. Franklin, Stephen W. Turner and Sarath C. Ranganathan on behalf of AREST CF.

Published in the American Journal of Respiratory and Critical Care Medicine in December 2008. 

 

Clinical trials in infants with cystic fibrosis detected following newborn screening.

Author: Stephen M. Stick

Published in the Paediatric Respiratory Reviews in September 2008. 

 

Early detection of lung disease in CF: do we have the necessary techniques?

Author: Peter D. Sly

Published in the Paediatric Respiratory Reviews in September 2008. 

 

Early detection of lung disease in children with cystic fibrosis using lung function.

Authors: Sarath Ranganathan, Barry Linnane, Gary Nolan, Catherine Gangell and Graham Hall.

Published in the Paediatric Respiratory Reviews in September 2008. 

 

Role of high-resolution computed tomography in the detection of early cystic fibrosis lung disease.

Authors: Barry Linnane, Phil Robinson, Sarath Ranganathan, Stephen Stick and Conor Murray.

Published in the Paediatric Respiratory Reviews in September 2008. 

 

Disease surveillance using bronchoalveolar lavage.

Authors: Siobhain Brennan, Catherine Gangell, Claire Wainwright and Peter D. Sly.

Published in the Paediatric Respiratory Reviews in September 2008.

Assessment of bronchodilator responsiveness in preschool children using forced oscillations. 

Authors: Thamrin C, Gangell CL, Udomittipong K, Kusel MMH, Patterson H, Fukushima T, Schultz A, Hall GL, Stick SM, Sly PD.

Published in Thorax in 2007. 

 

Respiratory impedance in children with cystic fibrosis using forced oscillations in clinic.

Authors: Gangell CL, Horak F, Jr., Patterson HJ, Sly PD, Stick SM, Hall GL.

Published in The European Respiratory Journal in 2007. 

 

The limitations of sweat electrolyte reference intervals for the diagnosis of cystic fibrosis: a systematic review.

Authors: Mishra A, Greaves R, Massie J.

Published in The Clinical biochemist Reviews / Australian Association of Clinical Biochemists in 2007. 

 

Community-wide screening for cystic fibrosis carriers could replace newborn screening for the diagnosis of cystic fibrosis.

Authors: Massie J, Forbes R, Dusart D, Bankier A, Delatycki MB.

Published in Journal of Paediatrics and Child Health in 2007. 

 

Longitudinal monitoring of pediatric cystic fibrosis lung disease using nitrite in exhaled breath condensate.

Authors: Horak F, Jr., Moeller A, Singer F, et al.

Published in Pediatric Pulmonology in 2007. 

 

Guidelines for implementation of cystic fibrosis newborn screening programs: Cystic Fibrosis Foundation workshop report.

Authors: Comeau AM, Accurso FJ, White TB, et al.

Published in Pediatrics in 2007. 

 

Pancreatic phenotype in infants with cystic fibrosis identified by mutation screening.

Authors: Cipolli M, Castellani C, Wilcken B, et al.

Published in Archives of disease in childhood in 2007. 

 

Exacerbations in cystic fibrosis: 2 prevention.

Authors: Bell SC, Robinson PJ.

Published in Thorax in 2007. 

Assay for urinary desmosines in a healthy pre-pubertal population using an improved extraction technique.

Authors: Winfield KR, Gard S, Kent GN, Sly PD, Brennan S.

Published in the Ann Clin Biochem in 2006. 

 

Inducible NO synthase expression is low in airway epithelium from young children with cystic fibrosis.

Authors: Moeller A, Horak F, Jr., Lane C, et al.

Published in Thorax in 2006. 

 

Exhaled nitric oxide is not reduced in infants with cystic fibrosis.

Authors: Franklin PJ, Hall GL, Moeller A, Horak F, Jr., Brennan S, Stick SM.

Published in The European Respiratory Journal in 2006. 

 

Changing their minds with time: a comparison of hypothetical and actual reproductive behaviors in parents of children with cystic fibrosis. 

Authors: Sawyer SM, Cerritelli B, Carter LS, Cooke M, Glazner JA, Massie J.

Published in Pediatrics in 2006. 

 

Markedly elevated neonatal immunoreactive trypsinogen levels in the absence of cystic fibrosis gene mutations is not an indication for further testing.

Authors: Massie J, Curnow L, Tzanakos N, Francis I, Robertson CF.

Published in Archives of disease in childhood in 2006. 

 

Pharmacokinetic profile of once daily intravenous tobramycin in children with cystic fibrosis.

Authors: Massie J, Cranswick N.

Published in Journal of Paediatrics and Child Health in 2006. 

 

Sweat testing for cystic fibrosis: How good is your laboratory?

Authors: Massie J,

Published in Journal of Paediatrics and Child Health in 2006. 

 

Parental attitudes to the identification of their infants as carriers of cystic fibrosis by newborn screening.

Authors: Lewis S, Curnow L, Ross M, Massie J.

Published in Journal of Paediatrics and Child Health in 2006. 

 

Clinical scoring systems in cystic fibrosis.

Authors: Hafen GM, Ranganathan SC, Robertson CF, Robinson PJ.

Published in Pediatric Pulmonology in 2006. 

Nasal wash as an alternative to bronchoalveolar lavage in detecting early pulmonary inflammation in children with cystic fibrosis.

Authors: Pitrez PM, Brennan S, Turner S, Sly PD.

Published in Respirology in 2005. 

 

CD14 C-159T and early infection with Pseudomonas aeruginosa in children with cystic fibrosis.

Authors: Martin AC, Laing IA, Zhang G, et al.

Published in Respiratory Research in 2005. 

 

Correlation of forced oscillation technique in preschool children with cystic fibrosis with pulmonary inflammation.

Authors: Brennan S, Hall GL, Horak F, et al.

Published in Thorax in 2005. 

 

Ventilation inhomogeneities in patients with cystic fibrosis: inappropriate reference data and errors?

Authors: Ranganathan SC, Robertson CF.

Published in American journal of respiratory and critical care medicine in 2005. 

 

The relevance of sweat testing for the diagnosis of cystic fibrosis in the genomic era.

Authors: Mishra A, Greaves R, Massie J.

Published in The Clinical biochemist Reviews / Australian Association of Clinical Biochemists in 2005. 

 

Diagnosis of cystic fibrosis after newborn screening: the Australasian experience--twenty years and five million babies later: a consensus statement from the Australasian Paediatric Respiratory Group.  

Authors: Massie J, Clements B.

Published in Pediatric Pulmonology in 2005. 

Detecting early lung disease in cystic fibrosis: are current techniques sufficient?

Authors: Sly PD, Brennan S.

Published in Thorax in 2004. 

 

Height and weight fail to detect early signs of malnutrition in children with cystic fibrosis.

Authors: Stapleton D, Kerr D, Gurrin L, Sherriff J, Sly P.

Published in Journal of pediatric gastroenterology and nutrition in 2001. 

 

Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin.

Authors: Brennan S, Cooper D, Sly PD.

Published in Thorax in 2001. 

 

What do children with cystic fibrosis and their parents know about nutrition and pancreatic enzymes?

Authors: Stapleton DR, Gurrin LC, Zubrick SR, Silburn SR, Sherriff JL, Sly PD.

Published in Journal of the American Dietetic Association in 2000. 

 

Macrolide antibiotics in diffuse panbronchiolitis and in cystic fibrosis.

Authors: Everard ML, Sly P, Brenan S, Ryan G.

Published in The European respiratory journal in 1997.