Ingrid Laing is a living example of the value of medical research. When she was born, her parents were told she would be lucky to make it to 20. But 42 years on - thanks to significant advancements in medical research - Ingrid is still here. Now known as Dr Laing, Ingrid is a respiratory researcher at The Telethon Kids Institute, working to increase the life expectancy of kids born today with her condition.
The Australian Respiratory Early Surveillance Team or AREST CF, based at the Telethon Kids Institute, has been short-listed for the 2015 Scopus Eureka Prize for Excellence in International Scientific Collaboration.
Cystic fibrosis on 7 News
Cystic fibrosis on 7 News
Our Director Professor Jonathan Carapetis is a guest reporter for 7 News in this video, which features our cystic fibrosis research.
Congratulations to AREST CF Students Kelly Martinovich and Renee Ng!
Kelly and Renee were both recipients of Best Poster Awards at the recent Institute of Respiratory Health 20 year anniversary Symposium in Perth.
Kelly's poster was titled "Antisense oligonucleotide mediated splice modulation to improve CFTR function of intron 9 5T polymorphism". Kelly’s PhD research has been developing antisense drugs that have potential to restore function to the CFTR protein and has some exciting impact for people with rare variants of CF.
Renee's poster was titled "Exploring the therapeutic potential of phage therapy to treat Pseudomonas aeruginosa infection in people with cystic fibrosis". Renee’s PhD research looks into establishing a screening tool for high throughput bacteriophage assessment and develop a potential therapeutic pipeline to treat children with bacterial lung infections.
Visiting collaborator from Emory University
In mid-November, Associate Professor Rabindra Tirouvanziam visited AREST CF from Emory University in Atlanta in the US state of Georgia. Funded by Telethon Kids Institute, this visit was part of an ongoing collaboration with Drs Luke Garratt, Anthony Kicic and Stephen Stick. Funded by the National Health and Medical Research Council, the collaboration is investigating how neutrophils respond to different early CF lung infections. Prior work by A/Prof Tirouvanziam found that neutrophils behave differently in the lungs of adults with CF, reducing their ability to beat infections. His recent work showed this behaviour can be corrected, offering a new type of treatment to help reduce lung damage in CF. The goal of AREST CF is to identify whether this neutrophil behaviour requires treatment early in disease, to help prevent chronic infections and lung damage. During his visit, the interim results from the collaborative study were reviewed and designs of future studies were confirmed. A/Prof Tirouvanziam also gave seminars at the Telethon Kids Institute and the Annual Rottnest Scientific Respiratory Meeting, hosted by the Respiratory Research Centre. Dr Garratt will be visiting Emory in May 2020 and we look to welcome A/Prof Tirouvanziam and his team again in the future.
Annual Rottnest Scientific Respiratory Meeting
It’s been a big month for the Institute’s Respiratory Research Centre!
Over 80 leading respiratory researchers and PhD students gathered in Rottnest Island for the Annual Rottnest Scientific Respiratory Meeting, hosted by the Institute’s Respiratory Research Centre.
The event, which has been going for the last 29 years, brings together researchers working in the area of paediatric respiratory health. This year, five prestigious international speakers joined the group, jetting in from Canada, the United States and the Netherlands.