What's happening
New drug therapy provides hope for kids with cystic fibrosis
New drug therapy provides hope for kids with cystic fibrosis
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Meet Sarah
Prestigious award for cystic fibrosis researcher
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AREST CF
Cystic fibrosis on 7 News
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Evening with CF Scientists 2019
An Evening with CF Scientists, 1st May 2019
This year we hosted 'An Evening with CF Scientists' on Wednesday the 1st of May 2019 in Perth in association with with Cystic Fibrosis WA and the Telethon Kids Institute.
Along with drinks, canapes and the opportunity to connect with Perth's CF community, the evening included laboratory tours and presentations.
Click below to watch the incredible presentations:
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An adaptive platform trial to improve outcomes in CF: André Schultz - CF Director, Respiratory Physician, PCH
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Emotional Wellbeing: A Community Approach: Kathryn Pekin - Services Manager, CFWA
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Potential of antisense oligonucleotides as a therapy for people with CF: Kelly Martinovich - PhD Candidate
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Living life to the full with with CF: Sophie Longton - Adult living with CF
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Should we treat fungal infections in early CF?: Dr Luke Garratt - Early Career Fellow
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Combating anti-microbial resistance - think outside the square!!: Dr Barry Clements - Honorary Research Fellow, Respiratory Physician, PCH
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Telethon Kids Respiratory Research Centre and wrap up: Prof Steve Stick - Head, P4 Respiratory Health for Kids, Respiratory Physician, PCH
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AREST CF recognised by the American Thoracic Society
Congratulations to our AREST CF researchers on having their Aspergillus Infections paper featured by the American Thoracic Society (ATS).
The paper titiled "Aspergillus Infections and Progression of Structural Lung Disease in Children with Cystic Fibrosis" was originally published in the American Journal of Respiratory and Critical Care Medicine in November 2019 and aimed to evaluate longitudinal associations between Aspergillus infections and lung disease in young children with CF.
Prof. Bob Hancock Visits from Canada
Pictured here is Dr Anthony Kicic, Respiratory Researcher at Telethon Kids & Prof Bob Hancock, Director of the Hancock Lab at @UBC.
Their research crosses the globe, using ‘Bob’s magic peptides’ to fight antibiotic-resistant superbugs in cystic fibrosis.
Check them out on Today Tonight!
Vision credit: Seven West Media and Today Tonight
AREST CF Students Win Awards
Congratulations to AREST CF Students Kelly Martinovich and Renee Ng!
Kelly and Renee were both recipients of Best Poster Awards at the recent Institute of Respiratory Health 20 year anniversary Symposium in Perth.
Kelly's poster was titled "Antisense oligonucleotide mediated splice modulation to improve CFTR function of intron 9 5T polymorphism". Kelly’s PhD research has been developing antisense drugs that have potential to restore function to the CFTR protein and has some exciting impact for people with rare variants of CF.
Renee's poster was titled "Exploring the therapeutic potential of phage therapy to treat Pseudomonas aeruginosa infection in people with cystic fibrosis". Renee’s PhD research looks into establishing a screening tool for high throughput bacteriophage assessment and develop a potential therapeutic pipeline to treat children with bacterial lung infections.
Visiting collaborator from Emory University
In mid-November, Associate Professor Rabindra Tirouvanziam visited AREST CF from Emory University in Atlanta in the US state of Georgia. Funded by Telethon Kids Institute, this visit was part of an ongoing collaboration with Drs Luke Garratt, Anthony Kicic and Stephen Stick. Funded by the National Health and Medical Research Council, the collaboration is investigating how neutrophils respond to different early CF lung infections. Prior work by A/Prof Tirouvanziam found that neutrophils behave differently in the lungs of adults with CF, reducing their ability to beat infections. His recent work showed this behaviour can be corrected, offering a new type of treatment to help reduce lung damage in CF. The goal of AREST CF is to identify whether this neutrophil behaviour requires treatment early in disease, to help prevent chronic infections and lung damage. During his visit, the interim results from the collaborative study were reviewed and designs of future studies were confirmed. A/Prof Tirouvanziam also gave seminars at the Telethon Kids Institute and the Annual Rottnest Scientific Respiratory Meeting, hosted by the Respiratory Research Centre. Dr Garratt will be visiting Emory in May 2020 and we look to welcome A/Prof Tirouvanziam and his team again in the future.
Annual Rottnest Scientific Respiratory Meeting
It’s been a big month for the Institute’s Respiratory Research Centre!
Over 80 leading respiratory researchers and PhD students gathered in Rottnest Island for the Annual Rottnest Scientific Respiratory Meeting, hosted by the Institute’s Respiratory Research Centre.
The event, which has been going for the last 29 years, brings together researchers working in the area of paediatric respiratory health. This year, five prestigious international speakers joined the group, jetting in from Canada, the United States and the Netherlands.
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